Choroid plexus papilloma account for less than 1% of all intracranial tumors, and usually occur in the first decade of life. The neoplastic cells were composed of strikingly regular cuboidal cells and seated on the underlying fibrovascular
stroma,
but
acinar structure, oncocytic change, or a mucin secreting variant have been rarely described in choroid plexus papilloma mostly by case reports. We present three cases of choroid plexus papilloma with one mucin secreting variant.
Case 1 was a 2 month-old female baby who was found to have a 3 to 2 cm sized lobulated mass in the third ventricle associated with hydrocephalus, and case 2 was a 17 year-old male who had a 2 to 2 cm sized mass in the fourth ventricle without
hydrocephalus. Case 3 was a 63 year-old female who had solid mass in the left frontoparietal lobe, which was recurred 13 years after tumor excision. Histologically, case 1 and 2 showed a pattern of typical choroid plexus papilloma and case 3
revealed a
mucin secreting variant of choroid plexus papilloma. In case 3, immunoreactivity against EMA, cytokeratin and vimentin supported that this case derive from the choroid plexus.
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